Batch Microbial Cultures: A Model That Can Account for Environment Changes

The so-called growth curve is of help to understand the underlying physiology microbial cultures. A number reported models describe observed trends and effects produced by changes culture environment. However, collected data (plate counts and/or Optical Density records) very often do not reliably comply with fitting parameters such models. An alternative semi empirical model describes experimental decay batch Major advantages include: reduced direct physical meaning best-fit parameters, easy comparison between different cultures environment conditions for a given strain. (either plate or OD allow estimation parameters: that why substantially applies any culture. present paper reports formal details its extension cases occurred because an exterior perturbation. seems adequate predictive microbiology investigations, as well studies on bactericidal drugs.